Back to search

Peptide record

TPDB66606

ACE inhibitor ACE inhibitors standard
4 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB66606
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 4-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
QSGP
Physicochemical Analysis
C15H25N5O7
ARNDCEHILKMFTWYV
QGPS
387.39
6.02
0
0
0
-0
1.17
-1.575
0.00
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
4
C15H25N5O7
387.39
6.02
-0
1.17
-1.575
387.3873
387.1748
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
168.60 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
O’Keeffe M. B., Norris R., Alashi M. A., Aluko R. E., FitzGerald R. J.
Peptide identification in a porcine gelatin prolyl endoproteinase hydrolysate with angiotensin converting enzyme (ACE) inhibitory and hypotensive activity. J. Funct. Foods, 34, 77–88, 2017
2017
Journal

Other

4
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CO)C(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)O InChI=1S/C15H25N5O7/c16-8(3-4-11(17)22)13(24)19-9(7-21)14(25)18-6-12(23)20-5-1-2-10(20)15(26)27/h8-10,21H,1-7,16H2,(H2,17,22)(H,18,25)(H,19,24)(H,26,27)/t8-,9-,10-/m0/s1 InChIKey: MFECBOKHZRZGAR-GUBZILKMSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/) ID: M02-001
Additional Detail Fields 1 fields
4