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Peptide record

TPDB66600

ACE inhibitor ACE inhibitors standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB66600
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 4-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
QGIH
Physicochemical Analysis
C19H31N7O6
ARNDCELKMFPSTWYV
QGHI
453.50
7.85
1
0
1
+0
1.24
-0.650
97.50
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
1
G
1
H
1
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 1 I: 1 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
4
C19H31N7O6
453.50
7.85
+0
1.24
-0.650
453.4915
453.2329
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
0.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Villegas J. M., Picariello G., Mamone G., Espeche Turbay M. B., Savoy de Giori G., Hebert E. M.
Milk-derived angiotensin-I-converting enzyme-inhibitory peptides generated by Lactobacillus delbrueckii subsp. lactis CRL 581. Peptidomics 1: 22–29, 2014.
2014
Journal

Other

4
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(CCC(N)=O)C(=O)NCC(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CC1=CN=CN1)C(O)=O InChI=1S/C19H31N7O6/c1-3-10(2)16(18(30)25-13(19(31)32)6-11-7-22-9-24-11)26-15(28)8-23-17(29)12(20)4-5-14(21)27/h7,9-10,12-13,16H,3-6,8,20H2,1-2H3,(H2,21,27)(H,22,24)(H,23,29)(H,25,30)(H,26,28)(H,31,32)/t10-,12-,13-,16-/m0/s1 InChIKey: HUYPHDHDDNUHIV-SDPXSBNPSA-N
Additional Detail Fields 1 fields
4