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Peptide record

TPDB66597

ACE inhibitor ACE inhibitors standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB66597
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 4-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
QDVL
Physicochemical Analysis
C20H35N5O8
ARNCEGHIKMFPSTWY
DQLV
473.53
3.10
0
1
2
-1
1.32
0.250
170.00
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
0
E
1
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
4
C20H35N5O8
473.53
3.10
-1
1.32
0.250
473.5192
473.2477
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
0.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Wu Q., Li Y., Peng K., Wang X. L., Ding Z., Liu L., Xu P., Liu G. Q.
Isolation and characterization of three antihypertension peptides from the mycelia of Ganoderma lucidum (Agaricomycetes). J. Agric. Food Chem., 67, 8149-8159, 2019
2019
Journal

Other

4
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CCC(=O)N)C(=O)N[C@@]([H])(CC(=O)O)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)O InChI=1S/C20H35N5O8/c1-9(2)7-13(20(32)33)24-19(31)16(10(3)4)25-18(30)12(8-15(27)28)23-17(29)11(21)5-6-14(22)26/h9-13,16H,5-8,21H2,1-4H3,(H2,22,26)(H,23,29)(H,24,31)(H,25,30)(H,27,28)(H,32,33)/t11-,12-,13-,16-/m0/s1 InChIKey: YVDHKEZQOSFSPC-QCQGSNGOSA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/) ID: M02-001
Additional Detail Fields 1 fields
4