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Peptide record

TPDB66593

ACE inhibitor ACE inhibitors standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB66593
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 5-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
PVLKD
Physicochemical Analysis
C26H46N6O8
ARNCEQGHIMFSTWY
DLKPV
570.69
6.75
1
1
2
-0
2.18
-0.200
136.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
1
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
1
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
5
C26H46N6O8
570.69
6.75
-0
2.18
-0.200
570.6770
570.3366
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
0.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Fan H., Wang J., Liao W., Jiang J., Wu J.
Identification and characterization of gastrointestinal-resistant angiotensin-converting enzyme inhibitory peptides from egg white proteins. J. Agric. Food Chem., 67, 7147−7156, 2019
2019
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(=O)O)C(=O)O InChI=1S/C26H46N6O8/c1-14(2)12-18(30-25(38)21(15(3)4)32-22(35)16-9-7-11-28-16)24(37)29-17(8-5-6-10-27)23(36)31-19(26(39)40)13-20(33)34/h14-19,21,28H,5-13,27H2,1-4H3,(H,29,37)(H,30,38)(H,31,36)(H,32,35)(H,33,34)(H,39,40)/t16-,17-,18-,19-,21-/m0/s1 InChIKey=HDZOQWQIJUQTAS-JLCRNFDHSA-N
Additional Detail Fields 1 fields
5