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Peptide record

TPDB66590

ACE inhibitor ACE inhibitors standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB66590
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 5-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
PSNPP
Physicochemical Analysis
C22H34N6O8
ARDCEQGHILKMFTWYV
P
510.55
6.02
0
0
0
-0
1.90
-1.820
0.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
2
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
3
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 3 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C22H34N6O8
510.55
6.02
-0
1.90
-1.820
510.5394
510.2430
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
192.27 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Escudero E., Mora L., Toldrá F.
Stability of ACE inhibitory ham peptides against heat treatment and in vitro digestion. Food Chemistry, 161, 305-311, 2014
2014
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)O InChI=1S/C22H34N6O8/c23-17(30)10-13(25-19(32)14(11-29)26-18(31)12-4-1-7-24-12)20(33)27-8-2-5-15(27)21(34)28-9-3-6-16(28)22(35)36/h12-16,24,29H,1-11H2,(H2,23,30)(H,25,32)(H,26,31)(H,35,36)/t12-,13-,14-,15-,16-/m0/s1 InChIKey= QOBXAMRQIQMYKX-QXKUPLGCSA-N
Additional Detail Fields 1 fields
5