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Peptide record

TPDB66573

ACE inhibitor ACE inhibitors standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB66573
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 5-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
PAPPK
Physicochemical Analysis
C24H40N6O6
RNDCEQGHILMFSTWYV
P
508.62
10.10
1
0
1
+1
2.17
-1.380
20.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
0
F
3
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 3 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C24H40N6O6
508.62
10.10
+1
2.17
-1.380
508.6094
508.3000
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
199.58 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Escudero E., Mora L., Toldrá F.
Stability of ACE inhibitory ham peptides against heat treatment and in vitro digestion. Food Chemistry, 161, 305-311, 2014
2014
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCCCN)C(=O)O InChI=1S/C24H40N6O6/c1-15(27-20(31)16-8-4-12-26-16)22(33)30-14-6-10-19(30)23(34)29-13-5-9-18(29)21(32)28-17(24(35)36)7-2-3-11-25/h15-19,26H,2-14,25H2,1H3,(H,27,31)(H,28,32)(H,35,36)/t15-,16-,17-,18-,19-/m0/s1 InChIKey= RAXUCYUMNKXMGS-VMXHOPILSA-N
Additional Detail Fields 1 fields
5