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Peptide record

TPDB66563

ACE inhibitor ACE inhibitors standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB66563
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 6-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
NGGPPT
Physicochemical Analysis
C22H35N7O9
ARDCEQHILKMFSWYV
GP
541.56
6.02
0
0
0
-0
1.48
-1.367
0.00
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
0
F
2
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 2 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C22H35N7O9
541.56
6.02
-0
1.48
-1.367
541.5534
541.2488
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
307.40 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5 MEROPS ID: S09.003)
ACE inhibitor
ah

Source & Reference

NA
Wei D., Fan W., Xu Y.
Identification of water-soluble peptides in distilled spent grain and its angiotensin converting enzyme (ACE) inhibitory activity based on UPLC-Q-TOF-MS and proteomics analysis. Food Chem., 353, 129521, 2021
2021
Journal

Other

6
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CC(=O)N)C(=O)NCC(=O)NCC(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])([C@]([H])(O)C)C(=O)O InChI=1S/C22H35N7O9/c1-11(30)18(22(37)38)27-20(35)13-4-2-7-29(13)21(36)14-5-3-6-28(14)17(33)10-25-16(32)9-26-19(34)12(23)8-15(24)31/h11-14,18,30H,2-10,23H2,1H3,(H2,24,31)(H,25,32)(H,26,34)(H,27,35)(H,37,38)/t11-,12+,13+,14+,18+/m1/s1 InChIKey=SWEFKAVJZMNXFK-LLLAAFKUSA-N
Additional Detail Fields 1 fields
6