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Peptide record

TPDB66561

ACE inhibitor ACE inhibitors standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB66561
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 3-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
NCW
Physicochemical Analysis
C18H23N5O5S1
ARDEQGHILKMFPSTYV
NCW
421.47
5.33
0
0
1
-0
-1.67
-0.633
0.00
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
5500
1304.95
2
Residue Composition
number
0
A
0
R
1
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
3
C18H23N5O5S1
421.47
5.33
-0
-1.67
-0.633
421.4709
421.1415
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
35.50 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Yu Z., Wu S., Zhao W., Ding L., Shiuan D., Chen F., Li J., Liu J.
Identification and the molecular mechanism of a novel myosin-derived ACE inhibitory peptide. Food and Function, 2018, 9, 364-370.
2018
Journal

Other

3
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(CC(N)=O)C(=O)N[C@@]([H])(CS)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(O)=O InChI=1S/C18H23N5O5S/c19-11(6-15(20)24)16(25)23-14(8-29)17(26)22-13(18(27)28)5-9-7-21-12-4-2-1-3-10(9)12/h1-4,7,11,13-14,21,29H,5-6,8,19H2,(H2,20,24)(H,22,26)(H,23,25)(H,27,28)/t11-,13-,14-/m0/s1 InChIKey=FGYUMGXLCZYNQG-UBHSHLNASA-N
Additional Detail Fields 1 fields
3