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Peptide record

TPDB66539

ACE inhibitor ACE inhibitors standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB66539
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 3-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
LRM
Physicochemical Analysis
C17H34N6O4S1
ANDCEQGHIKFPSTWYV
RLM
418.55
11.05
1
0
2
+1
0.02
0.400
130.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
1
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 1 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
3
C17H34N6O4S1
418.55
11.05
+1
0.02
0.400
418.5544
418.2355
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
0.15 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Kumagai Y., Toji K., Katsukura S., Morikawa R., Uji T., Yasui H., Shimizu T., Kishimura H.
Characterization of ACE inhibitory peptides prepared from Pyropia pseudolinearis protein. Marine Drugs, 19, 200, 2021
2021
Journal

Other

3
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N[C@@]([H])(CCSC)C(=O)O InChI=1S/C17H34N6O4S/c1-10(2)9-11(18)14(24)22-12(5-4-7-21-17(19)20)15(25)23-13(16(26)27)6-8-28-3/h10-13H,4-9,18H2,1-3H3,(H,22,24)(H,23,25)(H,26,27)(H4,19,20,21)/t11-,12-,13-/m0/s1 InChIKey: GPXFZVUVPCFTMG-AVGNSLFASA-N Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/) ID: M02-001
Additional Detail Fields 1 fields
3