Back to search

Peptide record

TPDB66533

ACE inhibitor ACE inhibitors iDPPIV standard
6 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB66533
ACE inhibitor
ACE inhibitors iDPPIV
Cardiometabolic peptides
Peptipedia iDPPIV
standard
No
A 6-aa standard natural multi-activity (ACE inhibitors and iDPPIV) peptide sequence curated from Peptipedia and iDPPIV, with an available 3D structural model.
Sequence
LPLPLL
Physicochemical Analysis
C34H60N6O7
ARNDCEQGHIKMFSTWYV
L
664.89
6.02
0
0
4
-0
-1.34
2.000
260.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
0
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C34H60N6O7
664.89
6.02
-0
-1.34
2.000
664.8738
664.4509
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
10.46 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Lin K., Zhang L., Han X., Cheng D.
Novel angiotensin I-converting enzyme inhibitory peptides from protease hydrolysates of Qula casein: Quantitative structure-activity relationship modeling and molecular docking study. J. Funct. Foods, 32, 266-277, 2017
2017
Journal

Other

6
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)O InChI=1S/C34H60N6O7/c1-19(2)15-23(35)32(44)39-13-9-11-27(39)31(43)37-25(17-21(5)6)33(45)40-14-10-12-28(40)30(42)36-24(16-20(3)4)29(41)38-26(34(46)47)18-22(7)8/h19-28H,9-18,35H2,1-8H3,(H,36,42)(H,37,43)(H,38,41)(H,46,47)/t23-,24-,25-,26-,27-,28-/m0/s1 InChIKey=KTNPPDBWNBJXQB-QUQVWLGBSA-N
Additional Detail Fields 1 fields
6