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Peptide record

TPDB66501

ACE inhibitor ACE inhibitors standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB66501
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 5-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
KVLPG
Physicochemical Analysis
C24H44N6O6
ARNDCEQHIMFSTWY
GLKPV
512.65
10.10
1
0
2
+1
0.96
0.420
136.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
1
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
5
C24H44N6O6
512.65
10.10
+1
0.96
0.420
512.6410
512.3312
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
265.44 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Escudero E., Mora L., Toldrá F.
Stability of ACE inhibitory ham peptides against heat treatment and in vitro digestion. Food Chemistry, 161, 305-311, 2014
2014
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)NCC(=O)O InChI=1S/C24H44N6O6/c1-14(2)12-17(24(36)30-11-7-9-18(30)22(34)27-13-19(31)32)28-23(35)20(15(3)4)29-21(33)16(26)8-5-6-10-25/h14-18,20H,5-13,25-26H2,1-4H3,(H,27,34)(H,28,35)(H,29,33)(H,31,32)/t16-,17-,18-,20-/m0/s1 InChIKey= NKAHMPATCUKYDM-JPLJXNOCSA-N
Additional Detail Fields 1 fields
5