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Peptide record

TPDB66472

ACE inhibitors standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB66472
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 9-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
IQSQPQAFP
Physicochemical Analysis
C46H70N12O14
RNDCEGHLKMTWYV
Q
1015.13
6.02
0
0
3
-0
1.16
-0.600
54.44
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
4
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
3
Q
0
G
0
H
1
I
0
L
0
K
0
M
1
F
2
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 3 G: 0 H: 0 I: 1 L: 0 K: 0 M: 0 F: 1 P: 2 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C46H70N12O14
1015.13
6.02
-0
1.16
-0.600
1015.1172
1014.5118
Evidence Records 1 records
Evidence 1 Activity

Activity

EC50
ACE inhibitors
630.00 µM
ACE inhibitor
ah

Source & Reference

NA
Kohmura M., Nio N., Ariyoshi Y.
Inhibition of angiotensin-converting enzyme by synthetic peptide fragments of various beta-caseins. Agric.Biol.Chem. 54(4),1101-1102(1990)
1990
Journal

Other

9
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](C)(CC)[C@]([H])(N)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N1CCC[C@@]1([H])C(O)=O InChI=1S/C46H70N12O14/c1-4-24(2)37(50)43(68)53-28(15-18-35(48)61)40(65)56-31(23-59)41(66)54-29(16-19-36(49)62)44(69)57-20-8-12-32(57)42(67)52-27(14-17-34(47)60)39(64)51-25(3)38(63)55-30(22-26-10-6-5-7-11-26)45(70)58-21-9-13-33(58)46(71)72/h5-7,10-11,24-25,27-33,37,59H,4,8-9,12-23,50H2,1-3H3,(H2,47,60)(H2,48,61)(H2,49,62)(H,51,64)(H,52,67)(H,53,68)(H,54,66)(H,55,63)(H,56,65)(H,71,72)/t24-,25-,27-,28-,29-,30-,31-,32-,33-,37-/m0/s1 InChIKey=AAKYFFALMYJXQM-QBJUYWHFSA-N
Additional Detail Fields 1 fields
9