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Peptide record

TPDB66471

ACE inhibitors standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB66471
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 9-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
IQSEPKAIP
Physicochemical Analysis
C44H75N11O14
RNDCGHLMFTWYV
IP
982.14
6.94
1
1
3
-0
3.83
-0.456
97.78
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
1
Q
0
G
0
H
2
I
0
L
1
K
0
M
0
F
2
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 0 I: 2 L: 0 K: 1 M: 0 F: 0 P: 2 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9
C44H75N11O14
982.14
6.94
-0
3.83
-0.456
982.1286
981.5477
Evidence Records 1 records
Evidence 1 Activity

Activity

EC50
ACE inhibitors
570.00 µM
ACE inhibitor
ah

Source & Reference

NA
Kohmura M., Nio N., Ariyoshi Y.
Inhibition of angiotensin-converting enzyme by synthetic peptide fragments of various beta-caseins. Agric.Biol.Chem. 54(4),1101-1102(1990)
1990
Journal

Other

9
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](C)(CC)[C@]([H])(N)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)N[C@]([H])(C(=O)N1CCC[C@@]1([H])C(O)=O)[C@@]([H])(C)CC InChI=1S/C44H75N11O14/c1-6-23(3)34(47)41(65)50-27(15-17-32(46)57)38(62)52-29(22-56)39(63)51-28(16-18-33(58)59)42(66)54-20-10-13-30(54)40(64)49-26(12-8-9-19-45)37(61)48-25(5)36(60)53-35(24(4)7-2)43(67)55-21-11-14-31(55)44(68)69/h23-31,34-35,56H,6-22,45,47H2,1-5H3,(H2,46,57)(H,48,61)(H,49,64)(H,50,65)(H,51,63)(H,52,62)(H,53,60)(H,58,59)(H,68,69)/t23-,24-,25-,26-,27-,28-,29-,30-,31-,34-,35-/m0/s1 InChIKey=NVQHMSQFSXSVIN-KKYHKPCUSA-N
Additional Detail Fields 1 fields
9