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Peptide record

TPDB66463

ACE inhibitor ACE inhibitors standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB66463
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 5-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
IKLPP
Physicochemical Analysis
C28H50N6O6
ARNDCEQGHMFSTWYV
P
566.74
10.10
1
0
2
+1
1.02
0.240
156.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
1
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 1 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C28H50N6O6
566.74
10.10
+1
1.02
0.240
566.7312
566.3780
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
193.90 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Escudero E., Mora L., Toldrá F.
Stability of ACE inhibitory ham peptides against heat treatment and in vitro digestion. Food Chemistry, 161, 305-311.
2014
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CC(C)C)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)O InChI=1S/C28H50N6O6/c1-5-18(4)23(30)25(36)31-19(10-6-7-13-29)24(35)32-20(16-17(2)3)26(37)33-14-8-11-21(33)27(38)34-15-9-12-22(34)28(39)40/h17-23H,5-16,29-30H2,1-4H3,(H,31,36)(H,32,35)(H,39,40)/t18-,19-,20-,21-,22-,23-/m0/s1 InChIKey= VBPRTIRRAFNLOP-LLINQDLYSA-N
Additional Detail Fields 1 fields
5