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Peptide record

TPDB66451

ACE inhibitor ACE inhibitors standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB66451
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 5-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
IAGRP
Physicochemical Analysis
C22H40N8O6
NDCEQHLKMFSTWYV
ARGIP
512.61
11.05
1
0
2
+1
0.79
-0.040
98.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C22H40N8O6
512.61
11.05
+1
0.79
-0.040
512.6014
512.3062
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
25.94 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Escudero E., Mora L., Toldrá F.
Stability of ACE inhibitory ham peptides against heat treatment and in vitro digestion. Food Chemistry, 161, 305-311, 2014
2014
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(C)C(=O)NCC(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)N1[C@@]([H])(CCC1)C(=O)O InChI=1S/C22H40N8O6/c1-4-12(2)17(23)19(33)28-13(3)18(32)27-11-16(31)29-14(7-5-9-26-22(24)25)20(34)30-10-6-8-15(30)21(35)36/h12-15,17H,4-11,23H2,1-3H3,(H,27,32)(H,28,33)(H,29,31)(H,35,36)(H4,24,25,26)/t12-,13-,14-,15-,17-/m0/s1 InChIKey= OTEIWGOISOJIFN-BWJWTDLKSA-N
Additional Detail Fields 1 fields
5