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Peptide record

TPDB66437

ACE inhibitor ACE inhibitors standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB66437
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 5-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
GPRGF
Physicochemical Analysis
C24H36N8O6
ANDCEQHILKMSTWYV
G
532.60
11.05
1
0
1
+1
0.15
-0.820
0.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C24H36N8O6
532.60
11.05
+1
0.15
-0.820
532.5912
532.2750
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
0.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Fu Y, Young JF, Rasmussen MK, Dalsgaard TK, Lametsch R, Aluko RE, Therkildsen M.
Angiotensin I–converting enzyme–inhibitory peptides from bovine collagen: insights into inhibitory mechanism and transepithelial transport. Food Res. Int. 89, 373–381, 2016
2016
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: NCC(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)N[C@@H](CC2=CC=CC=C2)C(=O)O InChI=1S/C24H36N8O6/c25-13-20(34)32-11-5-9-18(32)22(36)31-16(8-4-10-28-24(26)27)21(35)29-14-19(33)30-17(23(37)38)12-15-6-2-1-3-7-15/h1-3,6-7,16-18H,4-5,8-14,25H2,(H,29,35)(H,30,33)(H,31,36)(H,37,38)(H4,26,27,28)/t16-,17-,18-/m0/s1 InChIKey= MJBUJCWRACBOFZ-BZSNNMDCSA-N
Additional Detail Fields 1 fields
5