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Peptide record

TPDB66408

ACE inhibitor ACE inhibitors standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB66408
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 5-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
FPPQS
Physicochemical Analysis
C27H38N6O8
ARNDCEGHILKMTWYV
P
574.63
6.02
0
0
1
-0
0.48
-0.940
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
0
L
0
K
0
M
1
F
2
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 2 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C27H38N6O8
574.63
6.02
-0
0.48
-0.940
574.6245
574.2742
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
0.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Villegas J. M., Picariello G., Mamone G., Espeche Turbay M. B., Savoy de Giori G., Hebert E. M.
Milk-derived angiotensin-I-converting enzyme-inhibitory peptides generated by Lactobacillus delbrueckii subsp. lactis CRL 581. Peptidomics 1: 22–29, 2014.
2014
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(Cc1ccccc1)C(=O)N1CCC[C@@]1([H])C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CO)C(O)=O InChI=1S/C27H38N6O8/c28-17(14-16-6-2-1-3-7-16)25(38)33-13-5-9-21(33)26(39)32-12-4-8-20(32)24(37)30-18(10-11-22(29)35)23(36)31-19(15-34)27(40)41/h1-3,6-7,17-21,34H,4-5,8-15,28H2,(H2,29,35)(H,30,37)(H,31,36)(H,40,41)/t17-,18-,19-,20-,21-/m0/s1 InChIKey: CHYLWOAHXZNHFC-SXYSDOLCSA-N
Additional Detail Fields 1 fields
5