Back to search

Peptide record

TPDB66406

ACE inhibitor ACE inhibitors standard
4 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB66406
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 4-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
FLCT
Physicochemical Analysis
C22H34N4O6S1
ARNDEQGHIKMPSWYV
CLFT
482.60
5.33
0
0
2
-0
-1.79
2.100
97.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
0
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
4
C22H34N4O6S1
482.60
5.33
-0
-1.79
2.100
482.5933
482.2191
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
6.53 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Aiemratchanee P., Panyawechamontri K., Phaophu P., Reamtong O., Panbangred W.
In vitro antihypertensive activity of bioactive peptides derived from porcine blood corpuscle and plasma proteins. Int. J. Food Sci. Technol., 56, 2315–2324, 2021
2021
Journal

Other

4
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H]([C@H](O)C)C(=O)O InChI=1S/C22H34N4O6S/c1-12(2)9-16(24-19(28)15(23)10-14-7-5-4-6-8-14)20(29)25-17(11-33)21(30)26-18(13(3)27)22(31)32/h4-8,12-13,15-18,27,33H,9-11,23H2,1-3H3,(H,24,28)(H,25,29)(H,26,30)(H,31,32)/t13-,15+,16+,17+,18+/m1/s1 InChIKey=RFANMRCZKSKRJX-QSGXVVIFSA-N
Additional Detail Fields 1 fields
4