Back to search

Peptide record

TPDB66351

ACE inhibitor ACE inhibitors standard
4 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB66351
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 4-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
APYK
Physicochemical Analysis
C23H35N5O6
RNDCEQGHILMFSTWV
AKPY
477.56
9.74
1
0
2
+1
0.33
-1.250
25.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1490
312.00
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
0
F
1
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
4
C23H35N5O6
477.56
9.74
+1
0.33
-1.250
477.5525
477.2579
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
0.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Fan H., Wang J., Liao W., Jiang J., Wu J.
Identification and characterization of gastrointestinal-resistant angiotensin-converting enzyme inhibitory peptides from egg white proteins. J. Agric. Food Chem., 67, 7147−7156, 2019
2019
Journal

Other

4
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CC2=CC=C(C=C2)O)C(=O)N[C@@H](CCCCN)C(=O)O InChI=1S/C23H35N5O6/c1-14(25)22(32)28-12-4-6-19(28)21(31)27-18(13-15-7-9-16(29)10-8-15)20(30)26-17(23(33)34)5-2-3-11-24/h7-10,14,17-19,29H,2-6,11-13,24-25H2,1H3,(H,26,30)(H,27,31)(H,33,34)/t14-,17-,18-,19-/m0/s1 InChIKey=WWRSJFMVKXKSPS-QZHFEQFPSA-N
Additional Detail Fields 1 fields
4