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Peptide record

TPDB66349

ACE inhibitor ACE inhibitors standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB66349
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 4-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
APER
Physicochemical Analysis
C19H33N7O7
NDCQGHILKMFSTWYV
AREP
471.51
6.97
1
1
1
-0
3.11
-1.950
25.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
4
C19H33N7O7
471.51
6.97
-0
3.11
-1.950
471.5067
471.2434
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
530.21 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Salampessy J., Reddy N., Kailasapathy K., Phillips M.
Functional and potential therapeutic ACE-inhibitory peptides derived from bromelain hydrolysis of trevally proteins. J. Funct. Foods 14, 716-725
2015
Journal

Other

4
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O InChI=1S/C19H33N7O7/c1-10(20)17(31)26-9-3-5-13(26)16(30)24-11(6-7-14(27)28)15(29)25-12(18(32)33)4-2-8-23-19(21)22/h10-13H,2-9,20H2,1H3,(H,24,30)(H,25,29)(H,27,28)(H,32,33)(H4,21,22,23)/t10-,11-,12-,13-/m0/s1 InChIKey=ATDYYCAPQPTXQJ-CYDGBPFRSA-N
Additional Detail Fields 1 fields
4