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Peptide record

TPDB66347

ACE inhibitor ACE inhibitors standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB66347
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 5-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
AMNPP
Physicochemical Analysis
C22H36N6O7S1
RDCEQGHILKFSTWYV
P
528.62
6.02
0
0
2
-0
0.92
-0.600
20.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
1
M
0
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 1 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C22H36N6O7S1
528.62
6.02
-0
0.92
-0.600
528.6219
528.2358
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
304.50 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Escudero E., Mora L., Toldrá F.
Stability of ACE inhibitory ham peptides against heat treatment and in vitro digestion. Food Chemistry, 161, 305-311, 2014
2014
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(C)C(=O)N[C@@]([H])(CCSC)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N1[C@@]([H])(CCC1)C(=O)N1[C@@]([H])(CCC1)C(=O)O InChI=1S/C22H36N6O7S/c1-12(23)18(30)25-13(7-10-36-2)19(31)26-14(11-17(24)29)20(32)27-8-3-5-15(27)21(33)28-9-4-6-16(28)22(34)35/h12-16H,3-11,23H2,1-2H3,(H2,24,29)(H,25,30)(H,26,31)(H,34,35)/t12-,13-,14-,15-,16-/m0/s1 InChIKey= RYUIZKFXEBXESF-QXKUPLGCSA-N
Additional Detail Fields 1 fields
5