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Peptide record

TPDB66343

ACE inhibitor ACE inhibitors standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB66343
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
Peptipedia
standard
No
A 4-aa standard natural ace inhibitors peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
AERF
Physicochemical Analysis
C23H35N7O7
NDCQGHILKMPSTWYV
AREF
521.57
6.97
1
1
2
-0
1.53
-0.850
25.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
4
C23H35N7O7
521.57
6.97
-0
1.53
-0.850
521.5653
521.2590
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
0.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Fan H., Wang J., Liao W., Jiang J., Wu J.
Identification and characterization of gastrointestinal-resistant angiotensin-converting enzyme inhibitory peptides from egg white proteins. J. Agric. Food Chem., 67, 7147−7156, 2019
2019
Journal

Other

4
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)O InChI=1S/C23H35N7O7/c1-13(24)19(33)28-16(9-10-18(31)32)21(35)29-15(8-5-11-27-23(25)26)20(34)30-17(22(36)37)12-14-6-3-2-4-7-14/h2-4,6-7,13,15-17H,5,8-12,24H2,1H3,(H,28,33)(H,29,35)(H,30,34)(H,31,32)(H,36,37)(H4,25,26,27)/t13-,15-,16-,17-/m0/s1 InChIKey=XROSZQVIZWTKRM-HJWJTTGWSA-N
Additional Detail Fields 1 fields
4