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Peptide record

TPDB66315

ACE inhibitors standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB66315
ACE inhibitors
Cardiometabolic peptides
pep-lab Peptipedia
standard
No
A 8-aa standard natural ace inhibitors peptide sequence curated from pep-lab and Peptipedia, with an available 3D structural model.
Sequence
QSQPQAFP
Physicochemical Analysis
C40H59N11O13
RNDCEGHILKMTWYV
Q
901.97
6.02
0
0
2
-0
1.47
-1.238
12.50
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
0
0.00
4
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
3
Q
0
G
0
H
0
I
0
L
0
K
0
M
1
F
2
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 3 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 2 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C40H59N11O13
901.97
6.02
-0
1.47
-1.238
901.9600
901.4280
Evidence Records 1 records
Evidence 1 Activity

Activity

EC50
ACE inhibitors
700.00 µM
ACE inhibitor
ah

Source & Reference

NA
Kohmura M., Nio N., Ariyoshi Y.
Inhibition of angiotensin-converting enzyme by synthetic peptide fragments of various beta-caseins. Agric.Biol.Chem. 54(4),1101-1102(1990)
1990
Journal

Other

8
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(CCC(N)=O)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N1CCC[C@@]1([H])C(O)=O InChI=1S/C40H59N11O13/c1-21(33(56)48-26(19-22-7-3-2-4-8-22)39(62)51-18-6-10-29(51)40(63)64)45-35(58)24(12-15-31(43)54)46-37(60)28-9-5-17-50(28)38(61)25(13-16-32(44)55)47-36(59)27(20-52)49-34(57)23(41)11-14-30(42)53/h2-4,7-8,21,23-29,52H,5-6,9-20,41H2,1H3,(H2,42,53)(H2,43,54)(H2,44,55)(H,45,58)(H,46,60)(H,47,59)(H,48,56)(H,49,57)(H,63,64)/t21-,23-,24-,25-,26-,27-,28-,29-/m0/s1 InChIKey=NMJWPJGHORFIKE-XOBYPWAZSA-N
Additional Detail Fields 1 fields
8