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Peptide record

TPDB66291

ACE inhibitor ACE inhibitors standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB66291
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
pep-lab Peptipedia
standard
No
A 7-aa standard natural ace inhibitors peptide sequence curated from pep-lab and Peptipedia, with an available 3D structural model.
Sequence
KKYKVPQ
Physicochemical Analysis
C42H71N11O10
ARNDCEGHILMFSTW
K
890.09
10.46
3
0
2
+3
3.13
-1.986
41.43
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
167.40
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
0
L
3
K
0
M
0
F
1
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 3 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
7
C42H71N11O10
890.09
10.46
+3
3.13
-1.986
890.0780
889.5369
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
716.90 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Gómez-Ruiz J. A., Ramos M., Recio I.
Angiotensin-converting-enzyme-inhibitory peptides in Manchego cheeses manufactured with different starter cultures. Int. Dairy J. 2002, 12:697-706.
2002
Journal

Other

7
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(Cc1ccc(O)cc1)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCC(N)=O)C(O)=O InChI=1S/C42H71N11O10/c1-25(2)35(41(61)53-23-9-13-33(53)40(60)50-31(42(62)63)18-19-34(47)55)52-38(58)30(12-5-8-22-45)49-39(59)32(24-26-14-16-27(54)17-15-26)51-37(57)29(11-4-7-21-44)48-36(56)28(46)10-3-6-20-43/h14-17,25,28-33,35,54H,3-13,18-24,43-46H2,1-2H3,(H2,47,55)(H,48,56)(H,49,59)(H,50,60)(H,51,57)(H,52,58)(H,62,63)/t28-,29-,30-,31-,32-,33-,35-/m0/s1 InChIKey: IAWWAVIIOIOXPW-SIMWSORWSA-N
Additional Detail Fields 1 fields
7