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Peptide record

TPDB66288

ACE inhibitor from cuttlefish (Sepia officinalis) ACE inhibitors standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB66288
ACE inhibitor from cuttlefish (Sepia officinalis)
ACE inhibitors
Cardiometabolic peptides
pep-lab Peptipedia
standard
No
A 7-aa standard natural ace inhibitors peptide sequence curated from pep-lab and Peptipedia, with an available 3D structural model.
Sequence
GIHETTY
Physicochemical Analysis
C36H53N9O13
ARNDCQLKMFPSWV
T
819.87
5.13
1
1
2
-1
2.02
-0.757
55.71
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
1490
181.74
3
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
1
G
1
H
1
I
0
L
0
K
0
M
0
F
0
P
0
S
2
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 1 I: 1 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 2 W: 0 Y: 1 V: 0
Chemical Descriptors
7
C36H53N9O13
819.87
5.13
-1
2.02
-0.757
819.8564
819.3750
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
25.66 µM
ACE inhibitor
ah

Source & Reference

NA
Balti R., Bougatef A., Sila A., Guillochon D., Dhulster P., Nedjar-Arroume N.
Nine novel angiotensin I-converting enzyme (ACE) inhibitory peptides from cuttlefish (Sepia officinalis) muscle protein hydrolysates and antihypertensive effect of the potent active peptide in spontaneously hypertensive rats. Food Chemistry, 170, 519
2015
Journal

Other

7
Additional Detail Fields 1 fields
7