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Peptide record

TPDB66285

ACE inhibitor from cuttlefish (Sepia officinalis) ACE inhibitors standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB66285
ACE inhibitor from cuttlefish (Sepia officinalis)
ACE inhibitors
Cardiometabolic peptides
pep-lab Peptipedia
standard
No
A 7-aa standard natural ace inhibitors peptide sequence curated from pep-lab and Peptipedia, with an available 3D structural model.
Sequence
EKSYELP
Physicochemical Analysis
C39H60N8O14
ARNDCQGHIMFTWV
E
864.95
4.26
1
2
2
-1
4.11
-1.543
55.71
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
1490
172.26
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
2
E
0
Q
0
G
0
H
0
I
1
L
1
K
0
M
0
F
1
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 2 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
7
C39H60N8O14
864.95
4.26
-1
4.11
-1.543
864.9365
864.4214
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
14.41 µM
ACE inhibitor
ah

Source & Reference

NA
Balti R., Bougatef A., Sila A., Guillochon D., Dhulster P., Nedjar-Arroume N.
Nine novel angiotensin I-converting enzyme (ACE) inhibitory peptides from cuttlefish (Sepia officinalis) muscle protein hydrolysates and antihypertensive effect of the potent active peptide in spontaneously hypertensive rats. Food Chemistry, 170, 519
2015
Journal

Other

7
Additional Detail Fields 1 fields
7