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Peptide record

TPDB66279

ACE inhibitor ACE inhibitors standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB66279
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
pep-lab Peptipedia
standard
No
A 6-aa standard natural ace inhibitors peptide sequence curated from pep-lab and Peptipedia, with an available 3D structural model.
Sequence
TPTQQS
Physicochemical Analysis
C26H44N8O12
ARNDCEGHILKMFWYV
QT
660.68
6.02
0
0
0
-0
2.02
-1.800
0.00
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
5
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
2
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
1
S
2
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 1 T: 2 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C26H44N8O12
660.68
6.02
-0
2.02
-1.800
660.6722
660.3068
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
73.25 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Ni H., Li L. , Guo S.-S. , Li H.-H., Jiang R., Hu S.-Q.
Isolation and Identification of an Angiotensin-I Converting Enzyme Inhibitory Peptide from Yeast (Saccharomyces cerevisiae). Current Analytical Chemistry, 2012, 8, 180-185
2012
Journal

Other

6
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](C)(O)[C@]([H])(N)C(=O)N1CCC[C@@]1([H])C(=O)N[C@]([H])(C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CO)C(O)=O)[C@@]([H])(C)O InChI=1S/C26H44N8O12/c1-11(36)19(29)25(44)34-9-3-4-16(34)23(42)33-20(12(2)37)24(43)31-14(6-8-18(28)39)21(40)30-13(5-7-17(27)38)22(41)32-15(10-35)26(45)46/h11-16,19-20,35-37H,3-10,29H2,1-2H3,(H2,27,38)(H2,28,39)(H,30,40)(H,31,43)(H,32,41)(H,33,42)(H,45,46)/t11-,12-,13+,14+,15+,16+,19+,20+/m1/s1 InChIKey=QPGOKERSRKFQTI-CILRADMLSA-N
Additional Detail Fields 1 fields
6