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Peptide record

TPDB66272

ACE inhibitors standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB66272
ACE inhibitors
Cardiometabolic peptides
pep-lab Peptipedia
standard
No
A 6-aa standard natural ace inhibitors peptide sequence curated from pep-lab and Peptipedia, with an available 3D structural model.
Sequence
QPQAFP
Physicochemical Analysis
C32H46N8O9
RNDCEGHILKMSTWYV
QP
686.77
6.02
0
0
2
-0
0.76
-0.933
16.67
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
2
Q
0
G
0
H
0
I
0
L
0
K
0
M
1
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C32H46N8O9
686.77
6.02
-0
0.76
-0.933
686.7540
686.3377
Evidence Records 1 records
Evidence 1 Activity

Activity

EC50
ACE inhibitors
610.00 µM
ACE inhibitor
ah

Source & Reference

NA
Kohmura M., Nio N., Ariyoshi Y.
Inhibition of angiotensin-converting enzyme by synthetic peptide fragments of various beta-caseins. Agric.Biol.Chem. 54(4),1101-1102(1990)
1990
Journal

Other

6
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(CCC(N)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(Cc1ccccc1)C(=O)N1CCC[C@@]1([H])C(O)=O InChI=1S/C32H46N8O9/c1-18(27(43)38-22(17-19-7-3-2-4-8-19)31(47)40-16-6-10-24(40)32(48)49)36-28(44)21(12-14-26(35)42)37-29(45)23-9-5-15-39(23)30(46)20(33)11-13-25(34)41/h2-4,7-8,18,20-24H,5-6,9-17,33H2,1H3,(H2,34,41)(H2,35,42)(H,36,44)(H,37,45)(H,38,43)(H,48,49)/t18-,20-,21-,22-,23-,24-/m0/s1 InChIKey=YFNXYJCDPIUSJB-RTHQQOCOSA-N
Additional Detail Fields 1 fields
6