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Peptide record

TPDB66259

ACE inhibitor ACE inhibitors standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB66259
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
pep-lab Peptipedia
standard
No
A 6-aa standard natural ace inhibitors peptide sequence curated from pep-lab and Peptipedia, with an available 3D structural model.
Sequence
KAAAAP
Physicochemical Analysis
C23H41N7O7
RNDCEQGHILMFSTWYV
A
527.62
10.10
1
0
4
+1
0.76
0.283
66.67
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C23H41N7O7
527.62
10.10
+1
0.76
0.283
527.6127
527.3058
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
19.79 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Escudero E., Mora L., Toldrá F.
Stability of ACE inhibitory ham peptides against heat treatment and in vitro digestion. Food Chemistry, 161, 305-311, 2014
2014
Journal

Other

6
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)O InChI=1S/C23H41N7O7/c1-12(26-19(32)14(3)28-21(34)16(25)8-5-6-10-24)18(31)27-13(2)20(33)29-15(4)22(35)30-11-7-9-17(30)23(36)37/h12-17H,5-11,24-25H2,1-4H3,(H,26,32)(H,27,31)(H,28,34)(H,29,33)(H,36,37)/t12-,13-,14-,15-,16-,17-/m0/s1 InChIKey: XTNUCSHNHRPOAY-UYLCUJDWSA-N
Additional Detail Fields 1 fields
6