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Peptide record

TPDB66252

ACE inhibitor ACE inhibitors standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB66252
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
pep-lab Peptipedia
standard
No
A 6-aa standard natural ace inhibitors peptide sequence curated from pep-lab and Peptipedia, with an available 3D structural model.
Sequence
AAPLAP
Physicochemical Analysis
C25H42N6O7
RNDCEQGHIKMFSTWYV
A
538.64
6.02
0
0
4
-0
-0.17
1.000
115.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C25H42N6O7
538.64
6.02
-0
-0.17
1.000
538.6353
538.3105
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
14.38 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Escudero E., Mora L., Toldrá F.
Stability of ACE inhibitory ham peptides against heat treatment and in vitro digestion. Food Chemistry, 161, 305-311, 2014
2014
Journal

Other

6
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])(C)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)N[C@@]([H])(CC(C)C)C(=O)N[C@@]([H])(C)C(=O)N1[C@@]([H])(CCC1)C(=O)O InChI=1S/C25H42N6O7/c1-13(2)12-17(21(33)28-16(5)24(36)31-11-7-9-19(31)25(37)38)29-22(34)18-8-6-10-30(18)23(35)15(4)27-20(32)14(3)26/h13-19H,6-12,26H2,1-5H3,(H,27,32)(H,28,33)(H,29,34)(H,37,38)/t14-,15-,16-,17-,18-,19-/m0/s1 InChIKey= LWFRJHZOTQSLPG-DYKIIFRCSA-N
Additional Detail Fields 1 fields
6