Back to search

Peptide record

TPDB66247

ACE inhibitors standard
10 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB66247
ACE inhibitors
Cardiometabolic peptides
pep-lab Peptipedia
standard
No
A 10-aa standard natural ace inhibitors peptide sequence curated from pep-lab and Peptipedia, with an available 3D structural model.
Sequence
GIQSEPKAIP
Physicochemical Analysis
C46H78N12O15
RNDCHLMFTWYV
IP
1039.20
6.94
1
1
3
-0
3.84
-0.450
88.00
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
1
Q
1
G
0
H
2
I
0
L
1
K
0
M
0
F
2
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 1 H: 0 I: 2 L: 0 K: 1 M: 0 F: 0 P: 2 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C46H78N12O15
1039.20
6.94
-0
3.84
-0.450
1039.1798
1038.5691
Evidence Records 1 records
Evidence 1 Activity

Activity

EC50
ACE inhibitors
430.00 µM
ACE inhibitor
ah

Source & Reference

NA
Kohmura M., Nio N., Ariyoshi Y.
Inhibition of angiotensin-converting enzyme by synthetic peptide fragments of various beta-caseins. Agric.Biol.Chem. 54(4),1101-1102(1990)
1990
Journal

Other

10
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](C)(CC)[C@]([H])(NC(=O)CN)C(=O)N[C@@]([H])(CCC(N)=O)C(=O)N[C@@]([H])(CO)C(=O)N[C@@]([H])(CCC(O)=O)C(=O)N1CCC[C@@]1([H])C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C)C(=O)N[C@]([H])(C(=O)N1CCC[C@@]1([H])C(O)=O)[C@@]([H])(C)CC InChI=1S/C46H78N12O15/c1-6-24(3)36(55-34(61)22-48)43(69)52-28(15-17-33(49)60)40(66)54-30(23-59)41(67)53-29(16-18-35(62)63)44(70)57-20-10-13-31(57)42(68)51-27(12-8-9-19-47)39(65)50-26(5)38(64)56-37(25(4)7-2)45(71)58-21-11-14-32(58)46(72)73/h24-32,36-37,59H,6-23,47-48H2,1-5H3,(H2,49,60)(H,50,65)(H,51,68)(H,52,69)(H,53,67)(H,54,66)(H,55,61)(H,56,64)(H,62,63)(H,72,73)/t24-,25-,26-,27-,28-,29-,30-,31-,32-,36-,37-/m0/s1 InChIKey=MPCDNTCTNYNSTF-YOCSJFARSA-N
Additional Detail Fields 1 fields
10