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Peptide record

TPDB66246

ACE inhibitor ACE inhibitors standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB66246
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
pep-lab Peptipedia
standard
No
A 6-aa standard natural ace inhibitors peptide sequence curated from pep-lab and Peptipedia, with an available 3D structural model.
Sequence
INKVVR
Physicochemical Analysis
C32H61N11O8
ADCEQGHLMFPSTWY
V
727.91
11.49
2
0
3
+2
2.05
0.167
161.67
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
1
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
0
L
1
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
6
C32H61N11O8
727.91
11.49
+2
2.05
0.167
727.8932
727.4691
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
5.70 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Fan H., Wang J., Liao W., Jiang J., Wu J.
Identification and characterization of gastrointestinal-resistant angiotensin-converting enzyme inhibitory peptides from egg white proteins. J. Agric. Food Chem., 67, 7147−7156, 2019
2019
Journal

Other

6
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(C(C)C)C(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O InChI=1S/C32H61N11O8/c1-7-18(6)23(35)28(47)41-21(15-22(34)44)27(46)39-19(11-8-9-13-33)26(45)42-25(17(4)5)30(49)43-24(16(2)3)29(48)40-20(31(50)51)12-10-14-38-32(36)37/h16-21,23-25H,7-15,33,35H2,1-6H3,(H2,34,44)(H,39,46)(H,40,48)(H,41,47)(H,42,45)(H,43,49)(H,50,51)(H4,36,37,38)/t18-,19-,20-,21-,23-,24-,25-/m0/s1 InChIKey=VGJKOWOHZUFFEN-XEYKCJAPSA-N
Additional Detail Fields 1 fields
6