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Peptide record

TPDB66221

ACE inhibitor ACE inhibitors standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB66221
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
FermFooDB Peptipedia
standard
No
A 5-aa standard natural ace inhibitors peptide sequence curated from FermFooDB and Peptipedia, with an available 3D structural model.
Sequence
ARHPH
Physicochemical Analysis
C26H40N12O6
NDCEQGILKMFSTWYV
H
616.68
11.05
3
0
1
+1
3.01
-2.140
20.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
2
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 2 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C26H40N12O6
616.68
11.05
+1
3.01
-2.140
616.6710
616.3186
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
15.63 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

FermFooDB
Donkor O. N., Henriksson A., Singh T. K., Vasiljevic T., Shah N. P.
ACE inhibitory activity of probiotic yoghurt. Int. Dairy J. 2007 17:1321-1331.
2007
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](C(N[C@](C(N[C@](C(N1[C@@](C(N[C@](C(=O)O)(Cc2[nH]cnc2)[H])=O)([H])CCC1)=O)(Cc1[nH]cnc1)[H])=O)(CCCNC(=N)N)[H])=O)(N)C InChI=1S/C26H40N12O6/c1-14(27)21(39)35-17(4-2-6-32-26(28)29)22(40)36-18(8-15-10-30-12-33-15)24(42)38-7-3-5-20(38)23(41)37-19(25(43)44)9-16-11-31-13-34-16/h10-14,17-20H,2-9,27H2,1H3,(H,30,33)(H,31,34)(H,35,39)(H,36,40)(H,37,41)(H,43,44)(H4,28,29,32)/t14-,17-,18-,19-,20-/m0/s1 InChIKey: ZYTAKYZPVPECFS-HVRBKMHZSA-N
Additional Detail Fields 1 fields
5