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Peptide record

TPDB66219

ACE inhibitor ACE inhibitors standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB66219
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
FermFooDB Peptipedia
standard
No
A 5-aa standard natural ace inhibitors peptide sequence curated from FermFooDB and Peptipedia, with an available 3D structural model.
Sequence
RINKK
Physicochemical Analysis
C28H55N11O7
ADCEQGHLMFPSTWYV
K
657.81
11.64
3
0
1
+3
2.90
-2.260
78.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
1
Residue Composition
number
0
A
1
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C28H55N11O7
657.81
11.64
+3
2.90
-2.260
657.8036
657.4274
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
18.34 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

FermFooDB
Donkor O. N., Henriksson A., Singh T. K., Vasiljevic T., Shah N. P.
ACE inhibitory activity of probiotic yoghurt. Int. Dairy J. 2007 17:1321-1331.
2007
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: [H][C@](N)(CCCNC(N)=N)C(=O)N[C@@]([H])([C@@H](C)CC)C(=O)N[C@@]([H])(CC(N)=O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCCCN)C(O)=O InChI=1S/C28H55N11O7/c1-3-16(2)22(39-23(41)17(31)9-8-14-35-28(33)34)26(44)38-20(15-21(32)40)25(43)36-18(10-4-6-12-29)24(42)37-19(27(45)46)11-5-7-13-30/h16-20,22H,3-15,29-31H2,1-2H3,(H2,32,40)(H,36,43)(H,37,42)(H,38,44)(H,39,41)(H,45,46)(H4,33,34,35)/t16-,17-,18-,19-,20-,22-/m0/s1 InChIKey: CSGILLLPIGYBFJ-HVYFOGIKSA-N Antimicrobial peptide according to the MBPDB database
Additional Detail Fields 1 fields
5