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Peptide record

TPDB66218

ACE inhibitor ACE inhibitors standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB66218
ACE inhibitor
ACE inhibitors
Cardiometabolic peptides
FermFooDB Peptipedia
standard
No
A 5-aa standard natural ace inhibitors peptide sequence curated from FermFooDB and Peptipedia, with an available 3D structural model.
Sequence
TYKEE
Physicochemical Analysis
C29H44N6O12
ARNDCQGHILMFPSWV
E
668.70
4.26
1
2
1
-1
4.23
-2.580
0.00
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
1490
222.82
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
2
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
0
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 2 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
5
C29H44N6O12
668.70
4.26
-1
4.23
-2.580
668.6909
668.3006
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
18.58 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

FermFooDB
Donkor O. N., Henriksson A., Singh T. K., Vasiljevic T., Shah N. P.
ACE inhibitory activity of probiotic yoghurt. Int. Dairy J. 2007 17:1321-1331.
2007
Journal

Other

5
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])([C@]([H])(O)C)C(=O)N[C@@H](CC1=CC=C(C=C1)O)C(=O)N[C@@]([H])(CCCCN)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)N[C@@]([H])(CCC(=O)O)C(=O)O InChI=1S/C29H44N6O12/c1-15(36)24(31)28(45)35-21(14-16-5-7-17(37)8-6-16)27(44)32-18(4-2-3-13-30)25(42)33-19(9-11-22(38)39)26(43)34-20(29(46)47)10-12-23(40)41/h5-8,15,18-21,24,36-37H,2-4,9-14,30-31H2,1H3,(H,32,44)(H,33,42)(H,34,43)(H,35,45)(H,38,39)(H,40,41)(H,46,47)/t15-,18+,19+,20+,21+,24+/m1/s1 InChIKey=QEWIMXUOOARVNE-MXAMYCJDSA-N
Additional Detail Fields 1 fields
5