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Peptide record

TPDB66069

GE11 Tumor-homing Peptides standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB66069
GE11
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 21-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
YHWYGYTPQNVIGGGSGGGSC
Physicochemical Analysis
C96H130N26O30S1
ARDELKMF
G
2160.30
7.14
1
0
6
+0
-2.27
-0.500
32.38
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
9970
461.51
9
Residue Composition
number
0
A
0
R
1
N
0
D
1
C
0
E
1
Q
7
G
1
H
1
I
0
L
0
K
0
M
0
F
1
P
2
S
1
T
1
W
3
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 1 E: 0 Q: 1 G: 7 H: 1 I: 1 L: 0 K: 0 M: 0 F: 0 P: 1 S: 2 T: 1 W: 1 Y: 3 V: 1
Chemical Descriptors
21
C96H130N26O30S1
2160.30
7.14
+0
-2.27
-0.500
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Targeting
EGFR

Source & Reference

TumorHoPe2.0
TumorHoPe2
Epidermal growth factor receptor-targeted peptide conjugated phospholipid micelles for doxorubicin delivery
2016
Fan M et al. J Drug Target. 2016 24(2):111-9.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
SMMC-7721, MCF-7 cells
4-6 weeks old athymic BALB/c female nude mice
Phage display library
Doxorubicin, DSPE-PEG
Additional Detail Fields 3 fields
Doxorubicin, DSPE-PEG
SMMC-7721, MCF-7 cells
4-6 weeks old athymic BALB/c female nude mice