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Peptide record

TPDB66064

MGC Tumor-homing Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB66064
MGC
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 27-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: Amidated
Sequence
YEQDPWGVKWWYGYGMHTAPGTGTALS
Physicochemical Analysis
C143H192N34O40S1
RNCIF
G
3059.36
5.22
2
2
11
-1
-2.15
-0.696
32.59
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
20970
685.44
8
Residue Composition
number
2
A
0
R
0
N
1
D
0
C
1
E
1
Q
5
G
1
H
0
I
1
L
1
K
1
M
0
F
2
P
1
S
3
T
3
W
3
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 1 C: 0 E: 1 Q: 1 G: 5 H: 1 I: 0 L: 1 K: 1 M: 1 F: 0 P: 2 S: 1 T: 3 W: 3 Y: 3 V: 1
Chemical Descriptors
27
C143H192N34O40S1
3059.36
5.22
-1
-2.15
-0.696
Amidated
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Lung cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Utilizing glutathione-triggered nanoparticles to enhance chemotherapy of lung cancer by reprograming the tumor microenvironment
2018
Tao Cui et al. Int J Pharm. 2018 Dec 1 552(1-2):16-26

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
J774A.1 cells and A549 cells
male balb/c nude mice (20 ± 2 g),
Synthetic
Paclitaxel
Additional Detail Fields 3 fields
Paclitaxel
J774A.1 cells and A549 cells
male balb/c nude mice (20 ± 2 g),