Back to search

Peptide record

TPDB66058

Peptide18 Tumor-homing Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB66058
Peptide18
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 10-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
WREAAYQRFL
Physicochemical Analysis
C63H90N18O15
NDCGHIKMPSTV
AR
1339.52
9.87
2
1
6
+1
-0.60
-0.800
59.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
6990
521.83
2
Residue Composition
number
2
A
2
R
0
N
0
D
0
C
1
E
1
Q
0
G
0
H
0
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 2 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 1 V: 0
Chemical Descriptors
10
C63H90N18O15
1339.52
9.87
+1
-0.60
-0.800
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Breast cancer
αvβ3 integrin

Source & Reference

TumorHoPe2.0
TumorHoPe2
A robust optimization approach for the breast cancer targeted design of PEtOx-b-PLA polymersomes
2021
Umut Can Oz et al. Mater Sci Eng C Mater Biol Appl. 2021 Apr:123:111929.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
AU565 breast cancer cell line, MCF10A normal breast epithelial cell line
Synthetic
Doxorubicin (DOX), PEtOx-b-PLA polymersomes
Additional Detail Fields 2 fields
Doxorubicin (DOX), PEtOx-b-PLA polymersomes
AU565 breast cancer cell line, MCF10A normal breast epithelial cell line