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Peptide record

TPDB66056

ABB28 Tumor-homing Peptides standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB66056
ABB28
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 38-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: Amidation
Sequence
WQRPSSWGGLRSLGRKILRAWKKYGQRLGNQWAVGHLM-NH2
Physicochemical Analysis
C204H318N66O47S1
DCEFT
G
4479.24
12.59
9
0
15
+8
-0.91
-0.776
74.47
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
23490
524.42
8
Residue Composition
number
2
A
5
R
1
N
0
D
0
C
0
E
3
Q
6
G
1
H
1
I
5
L
3
K
1
M
0
F
1
P
3
S
0
T
4
W
1
Y
1
V
Amino Acid Distribution
A: 2 R: 5 N: 1 D: 0 C: 0 E: 0 Q: 3 G: 6 H: 1 I: 1 L: 5 K: 3 M: 1 F: 0 P: 1 S: 3 T: 0 W: 4 Y: 1 V: 1
Chemical Descriptors
38
C204H318N66O47S1
4479.24
12.59
+8
-0.91
-0.776
Amide
bombesin
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Lung, Breast, Colon, Prostate cancer
Gastrin-releasing peptide receptor

Source & Reference

TumorHoPe2.0
TumorHoPe2
Enhancing the circulating half-life and the antitumor effects of a tumor-selective cytotoxic peptide by exploiting endogenous serum albumin as a drug carrier
2016
Tao Su et al. Int J Pharm. 2016 Feb 29 499(1-2):195-204.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
COLO 205, K562, and SMMC-7721 tumor cells
Female athymic 4–5-week-old BALB/c mice
Synthetic
PEGylation, mitochondria-disrupting peptide
Additional Detail Fields 3 fields
PEGylation, mitochondria-disrupting peptide
COLO 205, K562, and SMMC-7721 tumor cells
Female athymic 4–5-week-old BALB/c mice