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Peptide record

TPDB66055

WV Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB66055
WV
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 12-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
WPYWNHHSHNNV
Physicochemical Analysis
C74H91N23O18
ARDCEQGILKMFT
NH
1590.68
8.01
3
0
4
+0
0.15
-1.783
24.17
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
12490
785.20
5
Residue Composition
number
0
A
0
R
3
N
0
D
0
C
0
E
0
Q
0
G
3
H
0
I
0
L
0
K
0
M
0
F
1
P
1
S
0
T
2
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 3 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 3 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 1 T: 0 W: 2 Y: 1 V: 1
Chemical Descriptors
12
C74H91N23O18
1590.68
8.01
+0
0.15
-1.783
SFEDRHWHHN
Evidence Records 2 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Breast cancer
Four-and-a-half LIM-only protein 3 (FHL3)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Selectively Suppressing Tumor Angiogenesis for Targeted Breast Cancer Therapy by Genetically Engineered Phage
2020
Li Y et al. Adv Mater. 2020 Jul 32(29):e2001260

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Nude mice bearing human MCF-7 breast tumors
Phage Display Library
Alexa Fluor
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Endothelial cell
Homing
Breast cancer
Four-and-a-half LIM-only protein 3, FHL3

Source & Reference

TumorHoPe2.0
TumorHoPe2
Selectively Suppressing Tumor Angiogenesis for Targeted Breast Cancer Therapy by Genetically Engineered Phage
2020
Li Y et al. Adv Mater.2020 Jul 32(29):e2001260

Other

Nude mice
Phage display library
Additional Detail Fields 2 fields
Alexa Fluor
Nude mice bearing human MCF-7 breast tumors Nude mice