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Peptide record

TPDB66054

anti-HER2 Tumor-homing Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB66054
anti-HER2
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 13-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
WNLPWYYSVSPTC
Physicochemical Analysis
C78H102N16O20S1
ARDEQGHIKMF
PSWY
1615.82
5.32
0
0
6
-0
-4.59
-0.223
52.31
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
13980
865.19
7
Residue Composition
number
0
A
0
R
1
N
0
D
1
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
2
P
2
S
1
T
2
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 2 S: 2 T: 1 W: 2 Y: 2 V: 1
Chemical Descriptors
13
C78H102N16O20S1
1615.82
5.32
-0
-4.59
-0.223
Evidence Records 2 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Breast cancer
HER2 receptor

Source & Reference

TumorHoPe2.0
TumorHoPe2
HER2 targeted biological macromolecule modified liposomes for improved efficacy of capecitabine in breast cancer
2020
Mantosh Kumar Singh et al. Int J Biol Macromol. 2020 May 1. 150(631-636)

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
MDA-MB453 cells
female Balb/C mice
Synthetic
cholesterol-acrylate
Evidence 2 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
Breast cancer
Her-2 and ErbB-2

Source & Reference

TumorHoPe2.0
TumorHoPe2
Tumor homing peptide modified liposomes of capecitabine for improved apoptotic activity and HER2 targeted therapy in breast cancer: in vitro studies
2019
Singh MK et al. RSC Adv. 2019 Aug 12 9(43):24987-24994

Other

MDA-MB453
Synthetic
Additional Detail Fields 3 fields
cholesterol-acrylate
MDA-MB453 cells MDA-MB453
female Balb/C mice