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Peptide record

TPDB66053

Tumor-homing Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB66053
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 7-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
N-terminal: tryptophans
Sequence
WHWRLPS
Physicochemical Analysis
C48H64N14O9
ANDCEQGIKMFTYV
W
981.12
11.05
2
0
3
+1
-1.91
-1.157
55.71
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
11000
1121.16
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
0
I
1
L
0
K
0
M
0
F
1
P
1
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 1 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
7
C48H64N14O9
981.12
11.05
+1
-1.91
-1.157
tryptophans
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
Neuroblastoma
human disialoganglioside GD2

Source & Reference

TumorHoPe2.0
TumorHoPe2
Identification and Tumour-Binding Properties of a Peptide with High Affinity to the Disialoganglioside GD2
2016
Jan Müller et al. PLoS One. 2016 Oct 7 11(10):e0163648.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
NMRI nude mice (6–8 weeks old)
Phage Display Library
M13 Ph.D.-7 phage display peptide library
Additional Detail Fields 2 fields
NMRI nude mice (6–8 weeks old)
M13 Ph.D.-7 phage display peptide library