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Peptide record

TPDB66051

F56 Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB66051
F56
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 12-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
VSWAFYHSKHPQ
Physicochemical Analysis
C71H95N19O17
RNDCEGILMT
HS
1486.65
9.74
3
0
5
+1
0.18
-0.867
32.50
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
6990
470.18
4
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
2
H
0
I
0
L
1
K
0
M
1
F
1
P
2
S
0
T
1
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 2 I: 0 L: 0 K: 1 M: 0 F: 1 P: 1 S: 2 T: 0 W: 1 Y: 1 V: 1
Chemical Descriptors
12
C71H95N19O17
1486.65
9.74
+1
0.18
-0.867
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell, Endothelial cell
Targeting
Breast cancer

Source & Reference

TumorHoPe2.0
TumorHoPe2
Lipid/PAA-coated mesoporous silica nanoparticles for dual-pH-responsive codelivery of arsenic trioxide/paclitaxel against breast cancer cells
2021
Bing-bing Zhang et al. Acta Pharmacol Sin. 2021 May 42(5):832-842.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
human umbilical vein endothelial cells (HUVECs), human breast carcinoma cell line MCF-7
female ICR mice
Polyacrylic acid (PAA), pH-sensitive lipid (PSL), Arsenic trioxide (ATO), Paclitaxel (PTX)
Additional Detail Fields 3 fields
Polyacrylic acid (PAA), pH-sensitive lipid (PSL), Arsenic trioxide (ATO), Paclitaxel (PTX)
human umbilical vein endothelial cells (HUVECs), human breast carcinoma cell line MCF-7
female ICR mice