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Peptide record

TPDB66038

Poly-siRNA Tumor-homing Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB66038
Poly-siRNA
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 7-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
VEGFTGC
Physicochemical Analysis
C30H45N7O11S1
ARNDQHILKMPSWY
G
711.79
3.29
0
1
2
-1
0.88
0.643
41.43
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
0
A
0
R
0
N
0
D
1
C
1
E
0
Q
2
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 1 E: 1 Q: 0 G: 2 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
7
C30H45N7O11S1
711.79
3.29
-1
0.88
0.643
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Targeting
CD31, Von Willebrand factor (vWF)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Tumor-homing poly-siRNA/glycol chitosan self-cross-linked nanoparticles for systemic siRNA delivery in cancer treatment
2012
So Jin Lee et al. Angew Chem Int Ed Engl. 2012 Jul 16 51(29):7203-7.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
RFP/B16F10 cells
SCC-7 tumor-bearing mice, PC-3 tumor-bearing mice
Synthetic
thiolated glycol chitosan (TGC)
Additional Detail Fields 3 fields
thiolated glycol chitosan (TGC)
RFP/B16F10 cells
SCC-7 tumor-bearing mice, PC-3 tumor-bearing mice