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Peptide record

TPDB66036

Tumor-homing Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB66036
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 10-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
TPHFLRIQNV
Physicochemical Analysis
C56H89N17O14
ADCEGKMSWY
RNQHILFPTV
1224.43
11.05
2
0
4
+1
1.43
-0.170
107.00
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
1
R
1
N
0
D
0
C
0
E
1
Q
0
G
1
H
1
I
1
L
0
K
0
M
1
F
1
P
0
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 1 L: 1 K: 0 M: 0 F: 1 P: 1 S: 0 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
10
C56H89N17O14
1224.43
11.05
+1
1.43
-0.170
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Endothelial vessel
Targeting
Glioblastoma
MAM, Ig domain, FNIII repeats

Source & Reference

TumorHoPe2.0
TumorHoPe2
Compositions and methods for treating cancer
2020
US 10745703 B2
US 10745703 B2

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
Human Glioblastoma Cell line LN-229, Gli36Δ5 human glioma cell line
NIH athymic nude female mice
Synthetic
nanoparticle
Additional Detail Fields 3 fields
nanoparticle
Human Glioblastoma Cell line LN-229, Gli36Δ5 human glioma cell line
NIH athymic nude female mice