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Peptide record

TPDB66035

TNYL Tumor-homing Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB66035
TNYL
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 12-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
N-terminal: (BOC)20
Sequence
TNYLFSPNGPIA
Physicochemical Analysis
C60H88N14O18
RDCEQHKMWV
NP
1293.44
5.94
0
0
5
-0
-1.09
-0.042
73.33
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
1490
115.20
5
Residue Composition
number
1
A
0
R
2
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
1
L
0
K
0
M
1
F
2
P
1
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 1 K: 0 M: 0 F: 1 P: 2 S: 1 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
12
C60H88N14O18
1293.44
5.94
-0
-1.09
-0.042
(BOC)20
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
EphB4

Source & Reference

TumorHoPe2.0
TumorHoPe2
TNYL peptide functional chitosan-g-stearate conjugate micelles for tumor specific targeting
2014
Chen F Y et al. Int J Nanomedicine.2014 Sep 26:9:4597-608

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
SKOV3
Male BALB/C+nu/F1 nude mice.
Synthetic
Doxorubicin (DOX)
Additional Detail Fields 3 fields
Doxorubicin (DOX)
SKOV3
Male BALB/C+nu/F1 nude mice.