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Peptide record

TPDB66024

GICP Tumor-homing Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB66024
GICP
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 7-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
N-terminal: Cysteine
Sequence
SSQPFWS
Physicochemical Analysis
C39H51N9O12
ARNDCEGHILKMTYV
S
837.89
6.02
0
0
2
-0
-1.56
-0.800
0.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
5500
656.41
4
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
0
L
0
K
0
M
1
F
1
P
3
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 1 S: 3 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
7
C39H51N9O12
837.89
6.02
-0
-1.56
-0.800
Cysteine
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Endothelial cell, Tumor cell, Tumor vessel
Homing
Glioma
NRP-1

Source & Reference

TumorHoPe2.0
TumorHoPe2
Enhanced glioma-targeting and stability of (L)GICP peptide coupled with stabilized peptide (D)A7R
2018
Zhang M et al. Acta Pharm Sin B. 2018 Jan 8(1):106-115.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
U87MG cells
nude mice
Synthetic
DA7R
Additional Detail Fields 3 fields
DA7R
U87MG cells
nude mice