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Peptide record

TPDB66016

AH1 Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB66016
AH1
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 9-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
SPSYVYHQF
Physicochemical Analysis
C54H70N12O15
ARNDCEGILKMTW
SY
1127.22
7.71
1
0
4
+0
-0.69
-0.611
32.22
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
2980
264.37
5
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
1
H
0
I
0
L
0
K
0
M
1
F
1
P
2
S
0
T
0
W
2
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 1 P: 1 S: 2 T: 0 W: 0 Y: 2 V: 1
Chemical Descriptors
9
C54H70N12O15
1127.22
7.71
+0
-0.69
-0.611
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Tumor cell
Homing
carcinoma cell
CT26

Source & Reference

TumorHoPe2.0
TumorHoPe2
Antibody-based Delivery of TNF to the Tumor Neovasculature Potentiates the Therapeutic Activity of a Peptide Anticancer Vaccine
2019
Probst P et al. Clin Cancer Res.2019 Jan 15 25(2):698-709.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
WEHI-164 fibrosarcoma, CT26 colon carcinoma cells
Eight-week-old female BALB/c mice
Synthetic
Additional Detail Fields 2 fields
WEHI-164 fibrosarcoma, CT26 colon carcinoma cells
Eight-week-old female BALB/c mice