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Peptide record

TPDB66015

AH5 Tumor-homing Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB66015
AH5
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 9-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
Sequence
SPSYAYHQF
Physicochemical Analysis
C52H66N12O15
RNDCEGILKMTWV
SY
1099.17
7.71
1
0
4
+0
-0.93
-0.878
11.11
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
2980
271.11
5
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
1
H
0
I
0
L
0
K
0
M
1
F
1
P
2
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 1 P: 1 S: 2 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
9
C52H66N12O15
1099.17
7.71
+0
-0.93
-0.878
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
Colorectal cancer
Phosphatidylserine(PS)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Annexin A5 as an immune checkpoint inhibitor and tumor-homing molecule for cancer treatment
2020
Kang T H et al. Nat Commun.2020 Feb 28 11(1):1137.

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
HPV16 E6 and E7 oncoproteins expressing murine tumor model, TC-1 tumor cells
6 - 8 weeks old C57BL/6, BALB/c mice
Synthetic
Additional Detail Fields 2 fields
HPV16 E6 and E7 oncoproteins expressing murine tumor model, TC-1 tumor cells
6 - 8 weeks old C57BL/6, BALB/c mice