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Peptide record

TPDB66012

Tumor-homing Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB66012
Tumor-homing Peptides
Cancer-related peptides
TumorHoPe2.0
standard
No
A 8-aa standard natural tumor-homing peptides peptide sequence curated from TumorHoPe2.0, with an available 3D structural model.
C-terminal: Cysteine
Sequence
SMSIARLC
Physicochemical Analysis
C35H65N11O11S2
NDEQGHKFPTWYV
S
880.09
9.01
1
0
4
+1
-0.44
1.050
110.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
1
R
0
N
0
D
1
C
0
E
0
Q
0
G
0
H
1
I
1
L
0
K
1
M
0
F
0
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 1 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 0 M: 1 F: 0 P: 0 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C35H65N11O11S2
880.09
9.01
+1
-0.44
1.050
Cysteine
Evidence Records 1 records
Evidence 1 Activity

Activity

Tumor-homing Peptides

Target

Homing
PECAM-1 (platelet endothelial cell adhesion molecule-1)

Source & Reference

TumorHoPe2.0
TumorHoPe2
Encapsulation of Doxorubicin in Furcellaran/Chitosan Nanocapsules by Layer-by-Layer Technique for Selectively Controlled Drug Delivery
2020
Milosavljevic V et al. Biomacromolecules.2020 Feb 10 21(2):418-434

Other

Source Activity Label Source Definition
Tumor-homing Peptides
TumorHoPe2.0 experimentally validated tumor-homing peptide annotation.
NT1A (normal adult prostatic epithelial cells), HEK 293 (human embryonic kidney cell line), MDA-MB-231, PC3
Synthetic
Doxorubicin (DOX)
Additional Detail Fields 2 fields
Doxorubicin (DOX)
NT1A (normal adult prostatic epithelial cells), HEK 293 (human embryonic kidney cell line), MDA-MB-231, PC3